Our Friends

Our day-to-day go-to authority for all matters biophysical, David is British Heart Foundation Professor of Cardiac Physiology at the University of Manchester. David is one of the world’s leading authorities on Ca²⁺ handling in cardiomyocytes and has published more papers in Circulation Research and the Journal of Physiology than anyone else that we know. He is currently the editor-in-chief of the Journal of General Physiology. The microvascular@manchester group are currently working through David’s incredible recent review of the physiology of intracellular Ca²⁺ buffering: available here.

Ingo is one of our closest collaborators at the University of Manchester and a leading scientist internationally in the field of in-vivo imaging. A physicist by training, Ingo is an expert in quantifying rodent brain blood flow using techniques such as laser speckle tracking and two photon microscopy via long term cemented cranial window, facilitating therapeutic interventional studies. Ingo is also renowned for the consistently high quality of his annual house parties for the Brain Inflammation Group (BIG): https://www.braininflamelab.org/

Stuart is Professor of Neuroscience at the University of Manchester and a renowned expert in the field of brain inflammation. Together with Ingo, Stuart has driven forward our studies on Vascular Dementia and Alzheimer’s disease. Stuart founded and co-leads the Geoffrey Jefferson Brain Research Centre which pulls together neuroscience research across Manchester in order to accelerate treatments for patients with stroke, brain cancer, dementia and Parkinson’s disease. https://gjbrainresearch.org/

Chris leads the Microvascular Research Unit at the Heart Research Institute in Sydney, Australia. Following his PhD in Nottingham, he worked in Oxford with Chris Garland and Kim Dora before moving to Sydney to work with Roland Stocker. In 2019, Chris published in Nature, showing that the Tryptophan derivative cis-WOOH activates Protein Kinase G and we now work with him in this area on the oxidative regulation of Calcium sparks.